Bee Venom

Ad El, D. D., Neuman, A., Wexler, M. R. and Eldad, A. (2002) Chronic facial edema caused by multiple bee stings: effective treatment with liposuction. Plastic and Reconstructive Surgery, 110(4), 1192-1193.

                Accession date: 9 June 2003. Call number: 638.178. Library code: X. Language: En. Author address: Dept of Plastic & Aesthetic Surgery, Hadassah Univ. Medical Center, Ein Kerem, POB 12000, Jerusalem 91120, Israel. Apicultural Abstracts from IBRA: AA558/04

honey bee venom/stings.

 Allan, S (2008) Allergy: Bee-keepers hold clues for T-cell tolerance.  Nature Reviews Immunology 8, 910  DOI:10.1038/nri2466.

Annila, I., Saarinen, J. V., Nieminen, M. M., Moilanen, E., Hahtola, P. and Harvima, I. T. (2000) Bee venom induces high histamine or high leukotriene C4 release in skin of sensitized beekeepers. Journal of Investigational Allergology & Clinical Immunology, 10(4), 223-228.

                Skin histamine and cysteinyl leukotriene release induced by bee venom were measured in 6 sensitized beekeepers using the skin microdialysis technique. The skin was dialysed for 2 h after skin prick test with bee venom, and the release of histamine and leukotriene C4 (LTC4 ) into the microdialysis fractions was measured. Leukotriene E4 (LTE4) and methylhistamine excretion into the urine was assayed, and whole blood histamine release test was performed. The release of histamine into the skin was variable; it correlated with release into whole blood. The 3 subjects with low histamine release exhibited high LTC4 release in the skin as well as high LTE4 excretion into the urine. Thus, the histamine and LTC4 releases were inversely associated with each other. These differences may explain the variation in the clinical reaction by bee stings in sensitized beekeepers . Accession date: 3 December 2001. Call number: 638.178. Library code: wf. Language: En, es. Author address: Clinic of Pulmonary Diseases, Tampere Univ. Hospital, PO Box 2000, FIN-33521 Tampere, Finland. Apicultural Abstracts from IBRA: AA541/02

honey bee venom/beekeepers/histamine/allergy.

Arcieri, E. S., França, E. T., Oliveria, H. B. d., Ferreira, L. d. A., Ferreira, M. A. and Rocha, F. J. (2002) Ocular lesions arising after stings by hymenopteran insects. Cornea, 21(3), 328-330.

                A patient who had been stung in the eye by a bee presented with corneal oedema and an inflammatory reaction of the anterior chamber with total regression of these alterations after clinical treatment. Accession date: 9 June 2003. Call number: 638.178. Library code: X. Language: En. Author address: Dept of Ophthalmology, School of Medicine, Federal Univ. of Uberlândia, MG, Brazil. Apicultural Abstracts from IBRA: AA560/04

stings/eyes/honey bee venom/human health.

Bachar, M. and Becker, O. M. (2000) Protein-induced membrane disorder: a molecular dynamics study of melittin in a dipalmitoylphosphatidylcholine bilayer. Biophysical Journal, 78(3), 1359-1375.

                A molecular dynamics simulation of melittin in a hydrated dipalmitoylphosphatidylcholine bilayer was performed. The simulation results show that the peptide affects the lower (intracellular) layer of the bilayer more strongly than the upper (extracellular) layer. The results can be interpreted as indicating an increased level of disorder and structural deformation for lower-layer phospholipids in the immediate vicinity of the peptide. In general, the simulation supports a role for local deformation and water penetration in melittin-induced lysis. Accession date: 18 April 2001. Call number: 638.178. Library code: wf. Language: En. Author address: School of Chemistry, Tel Aviv Univ., Ramat Aviv, Tel Aviv 69978, Israel. Apicultural Abstracts from IBRA: AA1210/01

honey bee venom/melittin/membranes/phospholipids.

Bahna, S. L. (2000) Insect sting allergy: a matter of life and death. Pediatric Annals, 29(12), 753-758.

                Accession date: 7 January 2003. Call number: 638.121.2. Library code: X. Language: En. Author address: Allergy/Immunology Training Program, Univ. of South Florida/All Children's Hospital, St. Petersburg, Box 6990, 801 Sixth Street South, St. Petersburg, FL 33701, USA. Apicultural Abstracts from IBRA: AA1010/02

Apis mellifera/Bombus/Vespula/Dolichovespula/stings/allergies/venoms

Bergamo, F. M. M., Biasi, F. d. and Sakate, M. (2000) Attack by Africanized bees: what to do? Caes & Gatos, 14(88), 16-21.

                Original title: Ataque de abelhas africanizadas: o que fazer?. The pathology and treatment of Africanized honey bee stings of dogs in Brazil are reviewed. Accession date: 24 November 2000. Call number: 638.121.2. Library code: X. Language: Pt. Author address: Faculdade de Medicina Veterinaria e Zootecnia (FMVZ), Universidade Estadual Paulista (UNESP), Botucatu, SP, Brazil. Apicultural Abstracts from IBRA: AA447/01

stings/dogs/Africanized honey bees/Brazil/venoms/composition.

Binder, M., Fierlbeck, G., King, T., Valent, P. and Bühring, H. J. (2002) Individual Hymenoptera venom compounds induce upregulation of the basophil activation marker ectonucleotide pyrophosphatase/phosphodiesterase 3 (CD203c) in sensitized patients. International Archives of Allergy and Immunology, 129 (2), 160-168.

                To analyse immediate-type hypersensitivity to defined hymenoptera venom components, a recently developed in vitro test was applied. The results show that flow-cytometric determination of CD203c upregulation on basophils activated by molecularly defined allergens is a powerful method to identify the precise allergen reactivity in sensitized individuals. Accession date: 20 May 2003. Call number: 638.178. Library code: wf. Language: En. Author address: Dept of Internal Medicine II, Division of Hematology and Immunology, Univ. of Tübingen, Tübingen, Germany. Apicultural Abstracts from IBRA: AA278/04

honey bee venom/allergies/allergens.

Borges, M. H., Soares, A. M., Rodrigues, V. M., Andrião Escarso, S. H., Diniz, H., Hamaguchi, A., Quintero, A., Lizano, S., Gutiérrez, J. M., Giglio, J. R. and Homsi Brandeburgo, M. I. (2000) Effects of aqueous extract of Casearia sylvestris (Flacourtiaceae) on actions of snake and bee venoms and on activity of phospholipases A2. Comparative Biochemistry and Physiology. B, Biochemistry & Molecular Biology, 127(1), 21-30.

                The crude aqueous extract from the leaves of this plant was assayed for its ability to inhibit phospholipase A2 (PLA2) activity and some biological activities of Apis mellifera venom, several snake venoms, and a number of isolated PLA2s. The extract induced partial inhibition of the PLA2 activity of venoms containing class I, II and III PLA2s; also it inhibited the anticoagulant activity of several isolated PLA2s. It is concluded that the plant leaves are a rich source of PLA2 inhibitors. Accession date: 28 November 2001. Call number: 638.178. Library code: X. Language: En. Author address: Departamento de Genética e Bioquímica, Universidade Federal de Uberlândia, UFU, 38400-902 Uberlândia-MG, Brazil. Apicultural Abstracts from IBRA: AA547/02

Apis mellifera/honey bee venom/venom/phospholipase A/Casearia/Flacourtiaceae/inhibition.